{"id":4270,"date":"2026-09-07T11:28:30","date_gmt":"2026-09-07T11:28:30","guid":{"rendered":"https:\/\/www.hygieia.com.cn\/?p=4270"},"modified":"2026-09-08T09:28:59","modified_gmt":"2026-09-08T09:28:59","slug":"ca-akg-joint-health","status":"publish","type":"post","link":"https:\/\/www.hygieia.com.cn\/?p=4270","title":{"rendered":"Ca-AKG\u7684\u4e0b\u4e00\u4e2a\u589e\u957f\u70b9\u51fa\u73b0\u4e86\uff1f\u5e0c\u5409\u4e9a\u9aa8\u5173\u8282\u7814\u7a76\u63ed\u793a\u5065\u5eb7\u8870\u8001\u7684\u65b0\u5e94\u7528\u8fb9\u754c"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">\u8fc7\u53bb\u51e0\u5e74\uff0c<a href=\"https:\/\/www.hygieia.com.cn\/?page_id=3591\">Ca-AKG<\/a> \u51e0\u4e4e\u59cb\u7ec8\u4e0e\u4e00\u4e2a\u5173\u952e\u8bcd\u7ed1\u5b9a \u2014\u2014Healthy Aging\uff08\u5065\u5eb7\u8870\u8001\uff09\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4ece TCA \u5faa\u73af\u3001\u80fd\u91cf\u4ee3\u8c22\uff0c\u5230\u8868\u89c2\u9057\u4f20\u4e0e\u7ec6\u80de\u7a33\u6001\uff0c\u03b1- \u916e\u620a\u4e8c\u9178\uff08AKG\uff09\u9010\u6e10\u6210\u4e3a\u5065\u5eb7\u8870\u8001\u9886\u57df\u5907\u53d7\u5173\u6ce8\u7684\u4ee3\u8c22\u7269\u30022026 \u5e74\u7684\u6700\u65b0\u7efc\u8ff0\u8fdb\u4e00\u6b65\u5c06\u5176\u5b9a\u4e49\u4e3a\u8fde\u63a5\u7ebf\u7c92\u4f53\u4ee3\u8c22\u3001\u7ec6\u80de\u7a33\u6001\u3001\u514d\u75ab\u8c03\u8282\u4e0e\u8868\u89c2\u9057\u4f20\u91cd\u5851\u7684\u91cd\u8981\u4ee3\u8c22\u4e0e\u4fe1\u53f7\u5206\u5b50 \u00b9\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4f46\u628a &#8220;\u5065\u5eb7\u8870\u8001&#8221; \u4ece\u6982\u5ff5\u843d\u56de\u771f\u5b9e\u751f\u6d3b\uff0c\u4e00\u4e2a\u66f4\u672c\u8d28\u7684\u95ee\u9898\u5c31\u4f1a\u6d6e\u73b0\uff1a\u4e00\u4e2a\u4eba\u662f\u5426\u771f\u6b63 &#8220;\u8001\u5f97\u5065\u5eb7&#8221;\uff0c\u7b54\u6848\u4ece\u6765\u4e0d\u53ea\u85cf\u5728\u4e00\u4e2a\u751f\u7269\u5e74\u9f84\u6570\u5b57\u91cc \u2014\u2014 \u9aa8\u9abc\u662f\u5426\u7a33\u5b9a\u3001\u5173\u8282\u80fd\u5426\u7075\u6d3b\u6d3b\u52a8\u3001\u808c\u8089\u662f\u5426\u4fdd\u6709\u529b\u91cf\u3001\u80fd\u5426\u957f\u671f\u7ef4\u6301\u884c\u52a8\u81ea\u5982\uff0c\u540c\u6837\u81f3\u5173\u91cd\u8981\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6b63\u662f\u8fd9\u79cd\u8ba4\u77e5\u7684\u8f6c\u53d8\uff0c\u8ba9\u8fd1\u5e74\u6765\u56f4\u7ed5 Ca-AKG \u7684\u7814\u7a76\u51fa\u73b0\u4e86\u4e00\u4e2a\u503c\u5f97\u4ea7\u4e1a\u5173\u6ce8\u7684\u65b9\u5411\u53d8\u5316\uff1a\u5065\u5eb7\u8870\u8001\u7684\u7814\u7a76\u89c6\u91ce\uff0c\u6b63\u4ece\u5355\u4e00\u7684\u751f\u7269\u5e74\u9f84\u6307\u6807\uff0c\u62d3\u5c55\u5230\u9aa8\u9abc\u3001\u5173\u8282\u3001\u808c\u8089\u4e0e\u884c\u52a8\u529b\u7b49\u771f\u5b9e\u529f\u80fd\u7ef4\u5ea6\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5e0c\u5409\u4e9a\u751f\u7269\u6b64\u524d\u5f00\u5c55\u7684 Enerlive\u00ae Ca-AKG \u9aa8\u5173\u8282\u7814\u7a76\uff0c\u6070\u597d\u5904\u5728\u8fd9\u4e00\u79d1\u5b66\u8d8b\u52bf\u53d8\u5316\u7684\u8282\u70b9\u4e0a\u3002<\/p>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-group has-background\" style=\"border-radius:8px;border-left-color:#0284c7;border-left-width:5px;background-color:#f0f9ff;padding-top:18px;padding-right:24px;padding-bottom:18px;padding-left:24px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-09ec5977 wp-block-group-is-layout-constrained\">\n<h3 class=\"wp-block-heading has-text-color\" style=\"color:#0369a1\"><em><strong>PART 01<\/strong><\/em> <strong>\u9aa8\u5173\u8282\uff0c\u6b63\u5728\u6210\u4e3aHealthy Aging\u4e0d\u80fd\u7ed5\u5f00\u7684\u4e00\u4e2a\u6838\u5fc3\u573a\u666f<\/strong><\/h3>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">\u9aa8\u5173\u8282\u5065\u5eb7\u5e76\u4e0d\u662f\u4e00\u4e2a\u5c0f\u4f17\u9700\u6c42\u3002GBD 2021\u9aa8\u5173\u8282\u708e\u7cfb\u7edf\u5206\u6790\u663e\u793a\uff0c2020\u5e74\u5168\u7403\u7ea6\u6709<strong>5.95\u4ebf\u4eba<\/strong>\u60a3\u9aa8\u5173\u8282\u708e\uff0c\u76f8\u5f53\u4e8e\u5168\u7403\u4eba\u53e3\u7684\u7ea67.6%\uff1b\u7814\u7a76\u9884\u6d4b\uff0c\u52302050\u5e74\uff0c\u4e0e2020\u5e74\u76f8\u6bd4\uff0c\u5168\u7403\u819d\u9aa8\u5173\u8282\u708e\u75c5\u4f8b\u53ef\u80fd\u589e\u957f\u7ea674.9%\uff0c\u9acb\u9aa8\u5173\u8282\u708e\u75c5\u4f8b\u53ef\u80fd\u589e\u957f\u7ea678.6%<sup>2<\/sup>\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e0e\u9700\u6c42\u7aef\u540c\u6b65\u53d8\u5316\u7684\uff0c\u662f\u6d88\u8d39\u5e02\u573a\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Grand View Research\u6700\u65b0\u5e02\u573a\u6570\u636e\u4f30\u8ba1\uff0c\u5168\u7403Bone &amp; Joint Health Supplements\uff08\u9aa8\u5173\u8282\u5065\u5eb7\u81b3\u98df\u8865\u5145\u5242\uff09\u5e02\u573a2024\u5e74\u89c4\u6a21\u7ea6\u4e3a<strong>142\u4ebf\u7f8e\u5143<\/strong>\uff0c\u9884\u8ba12026\u5e74\u7ea6162\u4ebf\u7f8e\u5143\uff0c\u5e76\u53ef\u80fd\u57282033\u5e74\u8fbe\u5230272\u4ebf\u7f8e\u5143\uff0c2025\u20142033\u5e74\u590d\u5408\u589e\u957f\u7387\u7ea67.6%<sup>3<\/sup>\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e0d\u53ea\u662f\u5e02\u573a\u89c4\u6a21\u589e\u957f\uff0c\u9aa8\u5173\u8282\u79d1\u5b66\u672c\u8eab\u4e5f\u5728\u53d1\u751f\u53d8\u5316\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2026\u5e74\u53d1\u8868\u4e8e&nbsp;<em>Signal Transduction and Targeted Therapy<\/em>&nbsp;\u7684\u7efc\u8ff0\u6307\u51fa\uff0c\u9aa8\u5173\u8282\u708e\u5df2\u7ecf\u4e0d\u80fd\u7b80\u5355\u7406\u89e3\u4e3a\u201c\u673a\u68b0\u78e8\u635f\u201d\uff0c\u5176\u53d1\u751f\u53d1\u5c55\u6d89\u53ca\u8f6f\u9aa8\u57fa\u8d28\u5931\u8861\u3001\u708e\u75c7\u3001\u4ee3\u8c22\u7d0a\u4e71\u3001\u8f6f\u9aa8\u4e0b\u9aa8\u91cd\u5851\u53ca\u591a\u79cd\u7ec6\u80de\u4fe1\u53f7\u7f51\u7edc<sup>4<\/sup>\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u53e6\u4e00\u9879\u7efc\u8ff0\u5219\u8fdb\u4e00\u6b65\u63d0\u51fa\uff0c\u9aa8\u5173\u8282\u708e\u6b63\u5728\u4ece\u4f20\u7edf\u7684\u5c40\u90e8\u201cwear-and-tear\uff08\u8001\u5316\u635f\u8017\uff09\u201d\u8ba4\u77e5\uff0c\u9010\u6e10\u8f6c\u5411\u4e0e<strong>\u4ee3\u8c22\u5931\u8c03\u3001\u7ebf\u7c92\u4f53\u529f\u80fd\u3001\u4f4e\u5ea6\u708e\u75c7\u548c\u5168\u8eab\u4ee3\u8c22\u72b6\u6001<\/strong>\u76f8\u8054\u7cfb\u7684\u75be\u75c5\u6a21\u578b<sup>5<\/sup>\u3002<\/p>\n\n\n\n<div class=\"wp-block-group has-text-color has-background\" style=\"border-radius:6px;color:#92400e;background-color:#fef3c7;padding-top:16px;padding-right:20px;padding-bottom:16px;padding-left:20px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-8e5f7a2f wp-block-group-is-layout-constrained\">\n<p class=\"wp-block-paragraph\">\u610f\u5473\u7740\u4e0b\u4e00\u4ee3\u9aa8\u5173\u8282\u8425\u517b\u53ef\u80fd\u4e0d\u4ec5\u4ec5\u662f<strong>\u201c\u7ed9\u8f6f\u9aa8\u8865\u4ec0\u4e48\uff1f\u201d<\/strong><strong>\uff0c<\/strong>\u8fd8\u9700\u8981\u8fdb\u4e00\u6b65\u56de\u7b54<strong>\u201c\u5982\u4f55\u652f\u6301\u8f6f\u9aa8\u7ec6\u80de\u6240\u5904\u7684\u4ee3\u8c22\u73af\u5883\uff1f\u201d\u3002<\/strong><\/p>\n<\/div><\/div>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter is-resized\"><img decoding=\"async\" src=\"https:\/\/www.hygieia.com.cn\/wp-content\/uploads\/2026\/09\/\u6587\u7ae01.png\" alt=\"\u9aa8\u5173\u8282\u708e\u7814\u7a76\u673a\u5236\u56fe\" style=\"aspect-ratio:1.7763679619349722;width:542px;height:auto\"\/><\/figure>\n<\/div>\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-group has-background\" style=\"border-radius:8px;border-left-color:#0284c7;border-left-width:5px;background-color:#f0f9ff;padding-top:18px;padding-right:24px;padding-bottom:18px;padding-left:24px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-09ec5977 wp-block-group-is-layout-constrained\">\n<h3 class=\"wp-block-heading has-text-color\" style=\"color:#0369a1\"><em><strong>PART 0<\/strong><\/em>2 <strong>\u4e3a\u4ec0\u4e48AKG\u4f1a\u8fdb\u5165\u9aa8\u4e0e\u5173\u8282\u7814\u7a76\u89c6\u91ce\uff1f<\/strong><\/h3>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">AKG\u4e0d\u4ec5\u53c2\u4e0e\u7ebf\u7c92\u4f53\u80fd\u91cf\u4ee3\u8c22\uff0c\u8fd8\u80fd\u591f\u5f71\u54cd\u7ec6\u80de\u6c27\u5316\u8fd8\u539f\u72b6\u6001\u3001\u514d\u75ab\u8c03\u8282\u3001\u4f4e\u6c27\u53cd\u5e94\u3001DNA\u53ca\u7ec4\u86cb\u767d\u4fee\u9970\u7b49\u8fc7\u7a0b\uff0c\u56e0\u6b64\u5176\u4f5c\u7528\u65e9\u5df2\u8d85\u51fa\u201cTCA\u5faa\u73af\u4e2d\u95f4\u4ea7\u7269\u201d\u7684\u8303\u7574<sup>1<\/sup>\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5728\u9aa8\u9abc\u9886\u57df\uff0c\u8fd9\u79cd\u5173\u7cfb\u5df2\u7ecf\u5f97\u5230\u8d8a\u6765\u8d8a\u7cfb\u7edf\u7684\u7814\u7a76\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2025\u5e74\u53d1\u8868\u4e8e&nbsp;<em>Acta Biochimica et Biophysica Sinica<\/em>&nbsp;\u7684\u4e13\u9898\u7efc\u8ff0\u603b\u7ed3\u8ba4\u4e3a\uff0cAKG\u53c2\u4e0e\u6210\u9aa8\u7ec6\u80de\u3001\u7834\u9aa8\u7ec6\u80de\u4ee5\u53ca\u9aa8\u7ec4\u7ec7\u4ee3\u8c22\u5e73\u8861\uff0c\u5176\u7814\u7a76\u5df2\u5ef6\u4f38\u81f3\u9aa8\u8d28\u758f\u677e\u3001\u9aa8\u5173\u8282\u708e\u3001\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\u7b49\u591a\u79cd\u9aa8\u76f8\u5173\u72b6\u6001<sup>6<\/sup>\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u66f4\u65e9\u7684\u52a8\u7269\u7814\u7a76\u53d1\u73b0\uff0c\u5728\u8001\u9f84\u52a8\u7269\u6a21\u578b\u4e2d\u8865\u5145AKG\u4e0e\u9aa8\u91cf\u589e\u52a0\u3001\u5e74\u9f84\u76f8\u5173\u9aa8\u91cf\u4e22\u5931\u51cf\u8f7b\u53ca\u9aa8\u9ad3\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6210\u9aa8\u6f5c\u80fd\u6062\u590d\u6709\u5173\uff1b\u7814\u7a76\u63d0\u51fa\u5176\u673a\u5236\u53ef\u80fd\u6d89\u53caH3K9me3\u3001H3K27me3\u7b49\u7ec4\u86cb\u767d\u7532\u57fa\u5316\u53d8\u5316\u4ee5\u53caBMP\u4fe1\u53f7\u8c03\u63a7<sup>7<\/sup>\u3002<\/p>\n\n\n\n<div class=\"wp-block-group has-background\" style=\"border-radius:6px;border-left-color:#2563eb;border-left-width:4px;background-color:#f8fafc;margin-top:20px;margin-bottom:20px;padding-top:20px;padding-right:24px;padding-bottom:20px;padding-left:24px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-1b0784f2 wp-block-group-is-layout-constrained\">\n<p class=\"wp-block-paragraph\">\u8fd9\u4e9b\u7814\u7a76\u5171\u540c\u5efa\u7acb\u4e86\u4e00\u6761\u903b\u8f91\u94fe\uff1a<strong>AKG \u2192 \u7ec6\u80de\u4ee3\u8c22 \u2192 \u6210\u9aa8\u80fd\u529b \u2192 \u5e74\u9f84\u76f8\u5173\u9aa8\u5065\u5eb7<\/strong>\u2014\u2014AKG \u5728\u9aa8\u9abc\u5065\u5eb7\u4e0e\u9aa8\u8d28\u758f\u677e\u9884\u9632\u4e2d\u7684\u6f5c\u529b\u7531\u6b64\u663e\u73b0\u3002\u800c\u4ee3\u8c22\u7684\u5f71\u54cd\u5e76\u4e0d\u6b62\u4e8e\u9aa8\uff1a\u8f6f\u9aa8\u7ec6\u80de\u540c\u6837\u4f9d\u8d56\u4ee3\u8c22\u73af\u5883\uff0c\u5176\u5931\u8861\u6b63\u662f\u9aa8\u5173\u8282\u708e\u7684\u5173\u952e\u73af\u8282\u3002\u5f53\u7814\u7a76\u89c6\u91ce\u5ef6\u4f38\u81f3\u8f6f\u9aa8\u4e0e\u9aa8\u5173\u8282\uff0c\u547d\u9898\u5df2\u4ece &#8220;\u7ed9\u8f6f\u9aa8\u8865\u4ec0\u4e48&#8221;\uff0c\u8f6c\u5411\u4ee5\u4ee3\u8c22\u652f\u6301\u5b88\u62a4\u6574\u4e2a\u9aa8\u5173\u8282\u7cfb\u7edf\u7684\u7a33\u6001\u3002<\/p>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">AKG\u4e0d\u4ec5\u662f\u9aa8\u9abc\u4ee3\u8c22\u7684\u53c2\u4e0e\u8005\uff0c\u66f4\u901a\u8fc7\u6297\u6c27\u5316\u3001\u6297\u94c1\u6b7b\u4ea1\u4e0e\u514d\u75ab \u2014 \u4ee3\u8c22\u8c03\u63a7\uff0c\u4e3a\u8f6f\u9aa8\u7ec6\u80de\u63d0\u4f9b\u4ee3\u8c22\u652f\u6301\u3002\u4ece\u9aa8\u9abc\u5230\u8f6f\u9aa8\uff0c\u4ece\u6210\u9aa8\u80fd\u529b\u5230\u8f6f\u9aa8\u7a33\u6001\uff0cAKG \u6307\u5411\u540c\u4e00\u6761\u4e3b\u7ebf \u2014\u2014 \u4ee5\u7ec6\u80de\u4ee3\u8c22\u4e3a\u652f\u70b9\uff0c\u652f\u6491\u5e74\u9f84\u76f8\u5173\u7684\u9aa8\u5173\u8282\u5065\u5eb7\u3002\u8fd9\u4e5f\u6b63\u662f Enerlive\u00ae Ca-AKG \u9aa8\u5173\u8282\u7814\u7a76\u6240\u5728\u7684\u65b9\u5411<sup>8-10<\/sup>\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/www.hygieia.com.cn\/wp-content\/uploads\/2026\/09\/\u6587\u7ae02-1024x576.png\" alt=\"\" class=\"wp-image-4272\" style=\"width:542px;height:auto\" srcset=\"https:\/\/www.hygieia.com.cn\/wp-content\/uploads\/2026\/09\/\u6587\u7ae02-1024x576.png 1024w, https:\/\/www.hygieia.com.cn\/wp-content\/uploads\/2026\/09\/\u6587\u7ae02-300x169.png 300w, https:\/\/www.hygieia.com.cn\/wp-content\/uploads\/2026\/09\/\u6587\u7ae02-768x432.png 768w, https:\/\/www.hygieia.com.cn\/wp-content\/uploads\/2026\/09\/\u6587\u7ae02.png 1080w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n<div class=\"wp-block-group has-background\" style=\"border-radius:8px;border-left-color:#0284c7;border-left-width:5px;background-color:#f0f9ff;padding-top:18px;padding-right:24px;padding-bottom:18px;padding-left:24px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-09ec5977 wp-block-group-is-layout-constrained\">\n<h3 class=\"wp-block-heading has-text-color\" style=\"color:#0369a1\"><em><strong>PART 0<\/strong><\/em>3 <strong>Enerlive\u00aeCa-AKG\u9aa8\u5173\u8282\u7814\u7a76\u771f\u6b63\u503c\u5f97\u770b\u7684\uff0c\u4e0d\u662f\u201c\u56db\u4e2a\u6307\u6807\u201d\uff0c\u800c\u662f\u4e00\u6761\u8bc1\u636e\u94fe<\/strong><\/h3>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">\u5e0c\u5409\u4e9a\u7814\u7a76\u4ee5\u9aa8\u5173\u8282\u708e\u6a21\u578b\u5927\u9f20\u4e3a\u5b9e\u9a8c\u5bf9\u8c61\uff0c\u901a\u8fc7\u68c0\u6d4b IL-6\u3001TNF-\u03b1\u3001MMP-13 \u53ca CTX-II \u7b49\u5173\u952e\u6307\u6807\uff0c\u63a2\u7a76Enerlive\u00ae Ca-AKG \u5bf9\u5173\u8282\u708e\u75c7\u4e0e\u8f6f\u9aa8\u635f\u4f24\u7684\u5e72\u9884\u6548\u679c\u3002\u7ed3\u679c\u8868\u660e\uff0cEnerlive\u00aeCa-AKG \u5177\u5907\u4f18\u5f02\u7684\u9aa8\u5173\u8282\u4fdd\u62a4\u6d3b\u6027\uff0c\u6574\u4f53\u529f\u6548\u4f18\u4e8e\u4f20\u7edf\u6d3b\u6027\u6210\u5206\u786b\u9178\u8f6f\u9aa8\u7d20\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u518d\u6b21\u56de\u770b\u8fd9\u7ec4\u6570\u636e\uff0c\u4f1a\u53d1\u73b0<strong>\u8fd9\u51e0\u4e2a\u6307\u6807\u5e76\u4e0d\u662f\u5b64\u7acb\u7684<\/strong><strong>\uff0c<\/strong>\u5b83\u4eec\u6070\u597d\u5206\u5e03\u5728\u4e0d\u540c\u5c42\u7ea7\uff1a<\/p>\n\n\n\n<div class=\"wp-block-group has-border-color has-background\" style=\"border-color:#e2e8f0;border-width:1px;border-radius:8px;background-color:#f8fafc;padding-top:20px;padding-right:20px;padding-bottom:20px;padding-left:20px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-7485b084 wp-block-group-is-layout-constrained\">\n<h4 class=\"wp-block-heading has-text-color\" style=\"color:#0284c7\"><strong>\u7b2c\u4e00\u5c42\uff1aTNF-\u03b1\u3001IL-6\u6c34\u5e73\u4e0b\u964d\uff0c\u6291\u5236\u708e\u75c7\u8fdb\u5c55<\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">\u5e0c\u5409\u4e9a\u5b9e\u9a8c\u4e2d\uff0c\u7ecf\u8fc7Enerlive\u00aeCa-AKG\u5e72\u9884\u540e\uff0c<strong>TNF-\u03b1<\/strong><strong>\u3001<\/strong><strong>IL-6<\/strong><strong>\u6c34\u5e73<\/strong><strong>\u76f8\u8f83\u6a21\u578b\u7ec4\u8fbe\u5230\u7edf\u8ba1\u5b66\u663e\u8457\u4e0b\u964d<\/strong>\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8fd9\u4e00\u6307\u6807\u4e4b\u6240\u4ee5\u91cd\u8981\uff0c\u662f\u56e0\u4e3a\u73b0\u4eca\u9aa8\u5173\u8282\u708e\u7814\u7a76\u4ecd\u7136\u628aTNF-\u03b1\u89c6\u4e3a\u8fde\u63a5\u5173\u8282\u708e\u75c7\u548c\u8f6f\u9aa8\u5206\u89e3\u4ee3\u8c22\u7684\u91cd\u8981\u4ecb\u8d28\u4e4b\u4e00\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7814\u7a76\u6307\u51fa\uff0cTNF-\u03b1\u80fd\u591f\u6fc0\u6d3bNF-\u03baB\u3001MAPK\u7b49\u4fe1\u53f7\uff0c\u5e76\u4e0a\u8c03MMPs\u53caADAMTS\u7b49\u57fa\u8d28\u964d\u89e3\u76f8\u5173\u86cb\u767d\uff0c\u540c\u65f6\u5f71\u54cd\u2161\u578b\u80f6\u539f\u7b49\u8f6f\u9aa8\u57fa\u8d28\u6210\u5206<sup>11<\/sup>\u3002&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6b64\u5916\uff0cTNF-\u03b1\u662f\u6838\u5fc3\u4fc3\u708e\u4fe1\u53f7\uff0c\u542f\u52a8\u5173\u8282\u5c40\u90e8\u708e\u75c7\uff0c\u7ee7\u800c\u8bf1\u5bfc IL-6 \u5927\u91cf\u91ca\u653e\uff0c\u4e8c\u8005\u5f62\u6210\u708e\u75c7\u7ea7\u8054\u653e\u5927\u6548\u5e94\uff0c\u5171\u540c\u4fc3\u8fdb\u8f6f\u9aa8\u964d\u89e3\u9176\u5206\u6ccc\u3001\u52a0\u901f\u8f6f\u9aa8\u7834\u574f\u3001\u6ed1\u819c\u589e\u751f\u3001\u5173\u8282\u75bc\u75db\u80bf\u80c0\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u76f8\u8f83\u4e8e\u6b63\u5e38\u5bf9\u7167\u7ec4\uff0c\u9aa8\u5173\u8282\u708e\u6a21\u578b\u5927\u9f20\u708e\u75c7\u56e0\u5b50\u542b\u91cf\u663e\u8457\u5347\u9ad8\u3002\u5728\u8fde\u7eed 28\u5929Enerlive\u00ae Ca-AKG\u704c\u80c3\u7ed9\u836f\u540e\uff0c\u5927\u9f20\u9aa8\u5173\u8282\u4e2d TNF-\u03b1\u3001IL-6 \u6c34\u5e73\u660e\u663e\u4e0b\u964d\uff0c\u4e14\u5176\u5bf9\u708e\u75c7\u56e0\u5b50\u7684\u6291\u5236\u6548\u679c\u4f18\u4e8e\u786b\u9178\u8f6f\u9aa8\u7d20\uff0c\u8bc1\u5b9e Ca-AKG \u5177\u5907\u826f\u597d\u7684\u6297\u708e\u6d3b\u6027\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><img decoding=\"async\" src=\"https:\/\/www.hygieia.com.cn\/wp-content\/uploads\/2026\/09\/\u6587\u7ae03.png\" alt=\"Enerlive\u00aeCa-AKG\u6291\u5236\u708e\u75c7\u8fdb\u5c55\"\/><figcaption class=\"wp-element-caption\"><strong>Enerlive\u00aeCa-AKG\u6291\u5236\u708e\u75c7\u8fdb\u5c55<\/strong><\/figcaption><\/figure>\n<\/div><\/div><\/div>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-group has-border-color has-background\" style=\"border-color:#e2e8f0;border-width:1px;border-radius:8px;background-color:#f8fafc;padding-top:20px;padding-right:20px;padding-bottom:20px;padding-left:20px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-7485b084 wp-block-group-is-layout-constrained\">\n<h4 class=\"wp-block-heading has-text-color\" style=\"color:#0284c7\"><strong>\u7b2c\u4e8c\u5c42\uff1aMMP-13\u3001CTX-II\u4e0b\u964d\uff0c\u8ba9\u201c\u8f6f\u9aa8\u5065\u5eb7\u201d\u8fd9\u6761\u903b\u8f91\u8fdb\u4e00\u6b65\u95ed\u5408<\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">\u5982\u679c\u53ea\u6709TNF-\u03b1\u3001IL-6\u53d8\u5316\uff0c\u90a3\u4e48Enerlive\u00aeCa-AKG\u7684\u7814\u7a76\u6545\u4e8b\u4ecd\u7136\u5f88\u5bb9\u6613\u505c\u7559\u5728\u201c\u708e\u75c7\u8c03\u8282\u201d\uff0cMMP-13\u3001 CTX-II \u7684\u53d8\u5316\uff0c\u8ba9\u201c\u8f6f\u9aa8\u5065\u5eb7\u201d\u8fd9\u6761\u903b\u8f91\u8fdb\u4e00\u6b65\u95ed\u5408\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5173\u8282\u8f6f\u9aa8\u7ec6\u80de\u5916\u57fa\u8d28\u4e3b\u8981\u7531\u2161\u578b\u80f6\u539f\u548c\u86cb\u767d\u805a\u7cd6\u7b49\u6784\u6210\uff0c\u800cMMP-13\u662f\u53c2\u4e0e\u2161\u578b\u80f6\u539f\u88c2\u89e3\u7684\u91cd\u8981\u80f6\u539f\u9176\u4e4b\u4e00\uff0c\u957f\u671f\u88ab\u89c6\u4e3a\u9aa8\u5173\u8282\u708e\u8f6f\u9aa8\u57fa\u8d28\u964d\u89e3\u7814\u7a76\u4e2d\u7684\u6838\u5fc3\u5206\u5b50<sup>12<\/sup>\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5f53\u8f6f\u9aa8\u57fa\u8d28\u964d\u89e3\u65f6\uff0c\u2161\u578b\u80f6\u539f\u76f8\u5173\u964d\u89e3\u7247\u6bb5 CTX-II \u53ef\u8fdb\u5165\u4f53\u6db2\u5faa\u73af\u3002\u901a\u8fc7\u68c0\u6d4bCTX-\u2161\u6c34\u5e73\u80fd\u591f\u53cd\u6620\u8f6f\u9aa8\u7279\u5f02\u6027\u964d\u89e3\u901f\u7387\uff0c\u662f\u8f6f\u9aa8\u635f\u4f24\u7684\u91d1\u6807\u51c6\u6807\u5fd7\u7269<sup>13<\/sup>\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5e0c\u5409\u4e9a\u7684Enerlive\u00aeCa-AKG\u5b9e\u9a8c\u7ed3\u679c\u663e\u793a\uff1a\u4e0e\u9aa8\u5173\u8282\u708e\u6a21\u578b\u7ec4\u76f8\u6bd4\uff0cCa-AKG\u7ec4\u4e0e\u786b\u9178\u8f6f\u9aa8\u7d20\u7ec4\u5927\u9f20MMP-13\u548cCTX-\u2161\u6c34\u5e73\u5747\u663e\u8457\u964d\u4f4e\uff0c\u5176\u4e2dCa-AKG\u7ec4\u5bf9MMP-13\u7684\u4e0b\u8c03\u4f5c\u7528\u66f4\u7a81\u51fa\uff0c<strong>MMP-13\u76f8\u8f83\u6a21\u578b\u7ec4\u8fbe\u5230\u7edf\u8ba1\u5b66\u663e\u8457\u4e0b\u964d\u3002<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"554\" height=\"286\" src=\"https:\/\/www.hygieia.com.cn\/wp-content\/uploads\/2026\/09\/\u6587\u7ae04.png\" alt=\"\" class=\"wp-image-4274\" srcset=\"https:\/\/www.hygieia.com.cn\/wp-content\/uploads\/2026\/09\/\u6587\u7ae04.png 554w, https:\/\/www.hygieia.com.cn\/wp-content\/uploads\/2026\/09\/\u6587\u7ae04-300x155.png 300w\" sizes=\"auto, (max-width: 554px) 100vw, 554px\" \/><\/figure>\n<\/div><\/div><\/div>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">\u503c\u5f97\u5173\u6ce8\u7684\u662f\uff0c\u5e0c\u5409\u4e9a\u8fd9\u4e00\u65b9\u5411\u4e0e\u56fd\u9645\u9aa8\u5173\u8282\u7814\u7a76\u51fa\u73b0\u4e86\u660e\u663e\u547c\u5e94\uff1aAKG\u7814\u7a76\u6b63\u5728\u8d8a\u6765\u8d8a\u591a\u5730\u6d89\u53ca\u6c27\u5316\u5e94\u6fc0\u3001\u8f6f\u9aa8\u7ec6\u80de\u6b7b\u4ea1\u3001\u94c1\u6b7b\u4ea1\u53ca\u7ec6\u80de\u5916\u57fa\u8d28\u7a33\u6001\uff0c\u800c\u6700\u65b0OA\u7814\u7a76\u4e5f\u8d8a\u6765\u8d8a\u91cd\u89c6\u708e\u75c7\u4e0e\u7ec6\u80de\u4ee3\u8c22\u3001\u8f6f\u9aa8\u57fa\u8d28\u964d\u89e3\u4e4b\u95f4\u7684\u8054\u52a8<sup>10,11<\/sup>\u3002<\/p>\n\n\n\n<div class=\"wp-block-group has-text-color has-background\" style=\"border-radius:6px;color:#1e40af;background-color:#eff6ff;padding-top:16px;padding-right:20px;padding-bottom:16px;padding-left:20px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-8e5f7a2f wp-block-group-is-layout-constrained\">\n<p class=\"wp-block-paragraph\">\u610f\u5473\u7740\uff0c<strong>\u5728\u5df2\u6709<\/strong><strong>AKG<\/strong><strong>\u9aa8\u5173\u8282\u56fd\u9645\u7814\u7a76\u57fa\u7840\u4e0a\uff0c\u589e\u52a0\u4e86\u4e00\u7ec4\u6765\u81eaEnerlive\u00aeCa-AKG\u539f\u6599\u7aef\u7684\u81ea\u4e3b\u4e34\u5e8a\u524d\u6570\u636e<\/strong>\u3002<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group has-background\" style=\"border-radius:8px;border-left-color:#0284c7;border-left-width:5px;background-color:#f0f9ff;padding-top:18px;padding-right:24px;padding-bottom:18px;padding-left:24px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-09ec5977 wp-block-group-is-layout-constrained\">\n<h3 class=\"wp-block-heading has-text-color\" style=\"color:#0369a1\"><em><strong>PART 0<\/strong><\/em>4 <strong>\u9aa8\u5173\u8282\u4f1a\u4e0d\u4f1a\u6210\u4e3aCa-AKG\u771f\u6b63\u7684\u201c\u4e0b\u4e00\u4e2a\u589e\u957f\u70b9\u201d\uff1f<\/strong><\/h3>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">\u6216\u8bb8\u73b0\u5728\u4e0b\u7ed3\u8bba\u8fd8\u4e3a\u65f6\u5c1a\u65e9\uff0c\u4f46\u4ece\u4ea7\u4e1a\u903b\u8f91\u6765\u770b\uff0c\u4e09\u4e2a\u4fe1\u53f7\u6b63\u5728\u540c\u65f6\u51fa\u73b0\u3002<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-1ea97505 wp-block-columns-is-layout-flex\" style=\"margin-top:20px;margin-bottom:20px\">\n<div class=\"wp-block-column has-border-color has-background is-layout-flow wp-block-column-is-layout-flow\" style=\"border-color:#e2e8f0;border-width:1px;border-radius:8px;background-color:#f8fafc;padding-top:16px;padding-right:16px;padding-bottom:16px;padding-left:16px\">\n<h4 class=\"wp-block-heading has-text-color\" style=\"color:#0f172a\"><strong>\u7b2c\u4e00\uff0c\u9700\u6c42\u6b63\u5728\u6269\u5927<\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">\u5168\u7403Bone &amp; Joint Health Supplements\uff08\u9aa8\u5173\u8282\u5065\u5eb7\u81b3\u98df\u8865\u5145\u5242\uff09\u5e02\u573a\u9884\u8ba1\u4ecd\u5c06\u4fdd\u6301\u589e\u957f\uff0c\u5e76\u4e14\u5e02\u573a\u5df2\u7ecf\u4ece\u4f20\u7edf\u9499\u548c\u7ef4\u751f\u7d20D\u8fdb\u4e00\u6b65\u6269\u5c55\u5230\u80f6\u539f\u86cb\u767d\u3001\u6c28\u7cd6\u3001\u8f6f\u9aa8\u7d20\u3001\u900f\u660e\u8d28\u9178\u7b49\u66f4\u591a\u5dee\u5f02\u5316\u65b9\u6848<sup>3<\/sup>\u3002<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column has-border-color has-background is-layout-flow wp-block-column-is-layout-flow\" style=\"border-color:#e2e8f0;border-width:1px;border-radius:8px;background-color:#f8fafc;padding-top:16px;padding-right:16px;padding-bottom:16px;padding-left:16px\">\n<h4 class=\"wp-block-heading has-text-color\" style=\"color:#0f172a\"><strong>\u7b2c\u4e8c\uff0c\u79d1\u5b66\u7814\u7a76\u65b9\u5411\u6b63\u5728\u53d1\u751f\u53d8\u5316<\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">2024\u20142026\u5e74\u7684\u7814\u7a76\u8d8a\u6765\u8d8a\u5f3a\u8c03\u9aa8\u5173\u8282\u708e\u80cc\u540e\u7684<strong>\u4ee3\u8c22\u3001\u708e\u75c7\u3001\u7ec6\u80de\u6b7b\u4ea1\u3001\u8f6f\u9aa8\u57fa\u8d28\u53ca\u514d\u75ab\u2014\u4ee3\u8c22\u4ea4\u4e92<\/strong>\uff0c\u8fd9\u4e3a\u4f20\u7edf\u201c\u7ed3\u6784\u8425\u517b\u201d\u4e4b\u5916\u7684\u539f\u6599\u63d0\u4f9b\u4e86\u65b0\u7684\u7814\u53d1\u7a7a\u95f4<sup>4,5<\/sup>\u3002<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column has-border-color has-background is-layout-flow wp-block-column-is-layout-flow\" style=\"border-color:#e2e8f0;border-width:1px;border-radius:8px;background-color:#f8fafc;padding-top:16px;padding-right:16px;padding-bottom:16px;padding-left:16px\">\n<h4 class=\"wp-block-heading has-text-color\" style=\"color:#0f172a\"><strong>\u7b2c\u4e09\uff0cAKG\u81ea\u8eab\u7684\u8bc1\u636e\u8fb9\u754c\u6b63\u5728\u6269\u5c55<\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">\u4ece\u9aa8\u5f62\u6210\u3001\u5e74\u9f84\u76f8\u5173\u9aa8\u91cf\uff0c\u5230\u9aa8\u5173\u8282\u708e\u3001\u8f6f\u9aa8\u7ec6\u80de\u94c1\u6b7b\u4ea1\u53caECM\u964d\u89e3\uff0cAKG\u5df2\u7ecf\u5f00\u59cb\u5177\u5907\u4eceHealthy Aging\u8fdb\u4e00\u6b65\u5ef6\u4f38\u5230Bone &amp; Joint Health\u7684\u79d1\u5b66\u57fa\u7840<sup>8,9<\/sup>\u3002<\/p>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading has-text-color\" style=\"color:#1e293b\"><strong>\u5bf9\u54c1\u724c\u548cODM\u800c\u8a00\uff0c\u8fd9\u4e2a\u65b0\u65b9\u5411\u610f\u5473\u7740\u4ec0\u4e48\uff1f<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Ca-AKG\u5982\u679c\u8fdb\u5165\u9aa8\u5173\u8282\u4ea7\u54c1\u5f00\u53d1\uff0c\u6ca1\u6709\u5fc5\u8981\u53bb\u590d\u5236\u4f20\u7edf\u6c28\u7cd6\u3001\u80f6\u539f\u86cb\u767d\u6216\u8005UC-II\u7684\u4ea7\u54c1\u903b\u8f91\u3002\u5b83\u771f\u6b63\u503c\u5f97\u63a2\u7d22\u7684\u5dee\u5f02\u5316\u4f4d\u7f6e\u53ef\u80fd\u662f\uff1a\u4ece\u201c\u7ed3\u6784\u8425\u517b\u201d\u589e\u52a0\u4e00\u4e2a\u201c\u4ee3\u8c22\u652f\u6301\u201d\u7ef4\u5ea6\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4f20\u7edf\u9aa8\u5173\u8282\u4ea7\u54c1\u66f4\u591a\u89e3\u51b3\uff1a<strong>Structural Nutrition\uff08\u7ed3\u6784\u6027\u8425\u517b\uff09<\/strong><strong>\uff0c<\/strong>\u4f8b\u5982\u4e3a\u9aa8\u9abc\u6216\u8f6f\u9aa8\u63d0\u4f9b\u8425\u517b\u652f\u6301\u3002\u800cCa-AKG\u672a\u6765\u53ef\u4ee5\u63a2\u7d22\u7684\u4ea7\u54c1\u4ef7\u503c\uff0c\u5219\u66f4\u591a\u6765\u81ea\uff1a<strong>Metabolic Support\uff08\u4ee3\u8c22\u652f\u6301\uff09<\/strong><strong>\uff0c<\/strong>\u5373\u4ece\u7ec6\u80de\u4ee3\u8c22\u3001\u6c27\u5316\u5e94\u6fc0\u548c\u8f6f\u9aa8\u5fae\u73af\u5883\u89d2\u5ea6\u5efa\u7acb\u65b0\u7684\u4ea7\u54c1\u6545\u4e8b\u3002<\/p>\n\n\n\n<div class=\"wp-block-columns are-vertically-aligned-center has-border-color has-background is-layout-flex wp-container-core-columns-is-layout-e27249b0 wp-block-columns-is-layout-flex\" style=\"border-color:#e2e8f0;border-width:1px;border-radius:12px;background-color:#f8fafc;margin-top:25px;margin-bottom:25px;padding-top:20px;padding-right:20px;padding-bottom:20px;padding-left:20px\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:35%\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><img decoding=\"async\" src=\"https:\/\/www.hygieia.com.cn\/wp-content\/uploads\/2026\/09\/AK5.jpg\" alt=\"Enerlive\u00ae Ca-AKG \u4ea7\u54c1\u5b9e\u7269\u56fe\"\/><\/figure>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:65%\">\n<p class=\"wp-block-paragraph\">\u56e0\u6b64\uff0c\u672a\u6765\u53ef\u80fd\u5f62\u6210\u7684\u7814\u53d1\u903b\u8f91\u4e0d\u662f\u201cCa-AKG\u66ff\u4ee3\u4f20\u7edf\u9aa8\u5173\u8282\u6210\u5206\u201d\uff0c\u800c\u662f\uff1a<strong>\u7ed3\u6784\u6027\u8425\u517b + \u4ee3\u8c22\u652f\u6301\uff0c<\/strong>\u4f8b\u5982\u4ece\u7814\u53d1\u601d\u8def\u4e0a\u5ef6\u4f38\uff0c\u8fdb\u4e00\u6b65\u56f4\u7ed5\uff1a<strong>Ca-AKG + Muscle Health Ingredients\uff08\u808c\u8089\u5065\u5eb7\u590d\u5408\u539f\u6599\uff09\uff0c<\/strong>\u6784\u5efa\u9762\u5411\u4e2d\u8001\u5e74\u4eba\u7fa4\u7684Bone + Joint + Muscle\u6574\u4f53\u65b9\u6848\u3002<\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-group has-background\" style=\"border-radius:8px;border-left-color:#0284c7;border-left-width:5px;background-color:#f0f9ff;padding-top:18px;padding-right:24px;padding-bottom:18px;padding-left:24px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-09ec5977 wp-block-group-is-layout-constrained\">\n<h3 class=\"wp-block-heading has-text-color\" style=\"color:#0369a1\"><em><strong>PART 0<\/strong><\/em>5 <strong>\u4eceBone &amp; Joint\u518d\u5f80\u524d\u4e00\u6b65\uff0c\u5176\u5b9e\u662f\u201cActive Aging\u201d<\/strong><\/h3>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Healthy Aging\u5982\u679c\u53ea\u505c\u7559\u5728\u201c\u5ef6\u7f13\u8870\u8001\u201d\u56db\u4e2a\u5b57\uff0c\u5f88\u5bb9\u6613\u53d8\u6210\u62bd\u8c61\u6982\u5ff5\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u800c\u5b9e\u9645\u5065\u5eb7\u5bff\u547d\u66f4\u9700\u8981\u843d\u5230\uff1a<strong>\u9aa8\u5173\u8282<\/strong><strong>\u3001<\/strong><strong>\u808c\u8089<\/strong><strong>\u3001<\/strong><strong>\u4ee3\u8c22<\/strong><strong>\uff0c<\/strong>\u6700\u7ec8\u6c47\u805a\u6210\uff1a<strong>\u884c\u52a8\u6d3b\u529b\u4e0e\u8eaf\u4f53\u673a\u80fd<\/strong><strong>\uff0c<\/strong>\u4e5f\u5c31\u662f\u2014\u2014\u8fd8\u80fd\u4e0d\u80fd\u8d70\u3001\u80fd\u4e0d\u80fd\u52a8\u3001\u80fd\u4e0d\u80fd\u7ef4\u6301\u72ec\u7acb\u751f\u6d3b\u80fd\u529b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5982\u679cCa-AKG\u672a\u6765\u80fd\u591f\u8fdb\u4e00\u6b65\u5efa\u7acb\u9aa8\u9abc\u3001\u5173\u8282\u3001\u808c\u8089\u53ca\u8eab\u4f53\u529f\u80fd\u5404\u65b9\u9762\u7684\u4eba\u4f53\u8bc1\u636e\uff0c\u5b83\u7684\u4ea7\u54c1\u5b9a\u4f4d\u5c31\u53ef\u80fd\u4ece\u5355\u7eaf\uff1a<strong>Longevity Ingredient\uff08\u957f\u5bff\u539f\u6599\uff09<\/strong>\u9010\u6b65\u6269\u5c55\u4e3a\uff1a<strong>Active Aging Ingredient\uff08\u6d3b\u529b\u8001\u9f84\u5316\u539f\u6599\uff09<\/strong><strong>\uff0c<\/strong>\u8fd9\u4f1a\u662f\u4e00\u4e2a\u6bd4\u5355\u72ec\u8bb2\u201c\u6297\u8870\u201d\u66f4\u5b8c\u6574\uff0c\u4e5f\u66f4\u5bb9\u6613\u843d\u5730\u5230\u6d88\u8d39\u9700\u6c42\u4e2d\u7684\u6545\u4e8b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4f46\u53ea\u662f\u628a\u5b9e\u9a8c\u505a\u6210\u4e00\u53e5\uff1a<strong>\u201cCa-AKG\u5177\u6709\u5065\u5eb7\u6297\u8870\u6f5c\u529b\u201d<\/strong><strong>\uff0c<\/strong>\u8fd9\u4e2a\u4ef7\u503c\u5f88\u5feb\u5c31\u4f1a\u88ab\u5e02\u573a\u590d\u5236\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u771f\u6b63\u5177\u6709\u957f\u671f\u58c1\u5792\u7684\u662f\uff1a\u673a\u5236\u7814\u7a76\u3001\u4e34\u5e8a\u524d\u8bc1\u636e\u3001\u4eba\u4f53\u4e34\u5e8a\u8bc1\u636e\u3001\u914d\u65b9\u4e0e\u5e94\u7528\uff0c\u4e5f\u5c31\u662f\u8ba9Ca-AKG\u7684\u6bcf\u4e00\u4e2a\u65b0\u5e94\u7528\u65b9\u5411\uff0c\u90fd\u6709\u9010\u6e10\u5347\u7ea7\u7684\u79d1\u5b66\u652f\u6491\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8fd9\u91cc\u4e5f\u662f\u5e0c\u5409\u4e9a\u4e0e\u666e\u901aCa-AKG\u4f9b\u5e94\u5546\u771f\u6b63\u53ef\u4ee5\u62c9\u5f00\u8ddd\u79bb\u7684\u5730\u65b9\u3002<\/p>\n\n\n\n<div class=\"wp-block-group has-background\" style=\"border-radius:8px;border-left-color:#2563eb;border-left-width:4px;background-color:#eff6ff;margin-top:20px;margin-bottom:20px;padding-top:20px;padding-right:24px;padding-bottom:20px;padding-left:24px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-1b0784f2 wp-block-group-is-layout-constrained\">\n<p class=\"wp-block-paragraph\"><a target=\"_blank\" href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzcwODA3OTQzOA==&amp;mid=2247484910&amp;idx=1&amp;sn=a237bb74988ae81ee8e4208767346c1a&amp;scene=21#wechat_redirect\" rel=\"noopener\">\u7531\u5e0c\u5409\u4e9a\u751f\u7269\u53d1\u8d77\u7684 Enerlive\u00aeCa\u2011AKG \u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167 RCT \u4eba\u4f53\u8bd5\u9a8c\uff08NCT07114536\uff09\u5df2\u5728 ClinicalTrials.gov \u5b8c\u6210\u6ce8\u518c\uff0c\u91cd\u70b9\u63a2\u7a76Enerlive\u00ae Ca\u2011AKG \u5bf9\u5065\u5eb7\u8870\u8001\u3001\u751f\u7269\u5e74\u9f84\u3001\u673a\u4f53\u529f\u80fd\u4e0e\u4ee3\u8c22\u5065\u5eb7\u7684\u4f5c\u7528\u3002<\/a><\/p>\n<\/div><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><img decoding=\"async\" src=\"https:\/\/mmbiz.qpic.cn\/mmbiz_png\/zkm5ibhm0ibkBMsxN8IyaGEsOWMdJG9Y1ysHxQAGpDLzVRBP0xgCmX6Y48ch6E8Y57gDNWXT954fSdDyUHwmzprqwQuWU5fw1a8ZXbsQeAVlA\/640?wx_fmt=png&amp;from=appmsg&amp;tp=wxpic&amp;wxfrom=5&amp;wx_lazy=1#imgIndex=11\" alt=\"RCT \u4eba\u4f53\u8bd5\u9a8c\u6ce8\u518c\u4fe1\u606f\"\/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">\u4ece\u9aa8\u5173\u8282\u65b9\u5411\u7684\u52a8\u7269\u5b9e\u9a8c\uff0c\u5ef6\u4f38\u81f3\u5065\u5eb7\u8870\u8001\u4eba\u7fa4\u7684\u4eba\u4f53\u4e34\u5e8a\u7814\u7a76\uff0c\u591a\u9879\u7814\u7a76\u5c42\u5c42\u9012\u8fdb\uff0c\u5171\u540c\u6784\u7b51\u4e86\u5e0c\u5409\u4e9a\u751f\u7269\u5173\u4e8e Enerlive\u00aeCa\u2011AKG \u7684\u5b8c\u6574\u79d1\u5b66\u8bc1\u636e\u4f53\u7cfb\u3002<\/p>\n\n\n\n<div class=\"wp-block-group has-background\" style=\"border-radius:8px;background-color:#f1f5f9;padding-top:20px;padding-right:24px;padding-bottom:20px;padding-left:24px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-2c7ddfe9 wp-block-group-is-layout-constrained\">\n<h3 class=\"wp-block-heading has-text-align-center has-text-color\" style=\"color:#0f172a\"><strong>\u7ed3\u8bed<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u89c2\u5bdf\u8fd1\u5e74\u6765\u7684\u79d1\u7814\u8f68\u8ff9\uff0cCa-AKG\u7684\u7814\u7a76\u6b63\u5728\u5411\u9aa8\u9abc\u548c\u5173\u8282\u6269\u5c55\uff1a\u4ece\u9aa8\u4ee3\u8c22\u548c\u6210\u9aa8\u80fd\u529b\uff0c\u5230\u7ebf\u7c92\u4f53\u4e0e\u6c27\u5316\u5e94\u6fc0\uff0c\u518d\u5230\u8f6f\u9aa8\u7ec6\u80de\u94c1\u6b7b\u4ea1\u548c\u7ec6\u80de\u5916\u57fa\u8d28\u7a33\u6001\uff0c\u4e00\u7cfb\u5217\u8bc1\u636e\u8868\u660e\uff0cCa\u2011AKG \u6b63\u5728\u8df3\u51fa \u201c\u5065\u5eb7\u8870\u8001\u4ee3\u8c22\u7269\u201d \u7684\u4f20\u7edf\u5b9a\u4f4d\uff0c\u8fdb\u4e00\u6b65\u62d3\u5c55\u81f3\u9aa8\u9abc\u517b\u62a4\u3001\u5173\u8282\u5065\u5eb7\u4e0e\u884c\u52a8\u673a\u80fd\u6539\u5584\uff0c\u6307\u5411Active Aging\uff08\u6d3b\u529b\u6297\u8870\uff09 \u7684\u5168\u65b0\u8d5b\u9053\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4f9d\u6258\u4ece\u57fa\u7840\u673a\u7406\u7814\u7a76\u5230\u4eba\u4f53 RCT \u4e34\u5e8a\u8bd5\u9a8c\u7684\u5b8c\u6574\u8bc1\u636e\u79ef\u7d2f\uff0c\u5e0c\u5409\u4e9aEnerlive\u00aeCa\u2011AKG \u4e0d\u518d\u5c40\u9650\u4e8e\u5355\u4e00\u6297\u8870\u6982\u5ff5\uff0c\u4e3a\u65b0\u4e00\u4ee3\u9aa8\u5173\u8282\u4e0e\u5065\u5eb7\u8870\u8001\u590d\u5408\u517b\u62a4\u539f\u6599\u5f00\u8f9f\u4e86\u5dee\u5f02\u5316\u521b\u65b0\u8def\u5f84\uff0c\u4e5f\u4e3a\u529f\u80fd\u6027\u81b3\u98df\u8865\u5145\u5242\u884c\u4e1a\u5e26\u6765\u5168\u65b0\u7814\u53d1\u601d\u8def\u3002<\/p>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">\u53c2\u8003\u6587\u732e\uff1a<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">[1] KornickaKontek K, Marycz K. AlphaKetoglutarate: A Metabolic Regulator of Cellular Homeostasis and Pathophysiology.&nbsp;<em>Biomedicines<\/em>, 2026.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">[2] GBD 2021 Osteoarthritis Collaborators. Global, regional, and national burden of osteoarthritis,1990\u20132020 and projections to 2050.\u300aThe Lancet Rheumatology\u300b\uff0c2023<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">[3]&nbsp;Grand View Research.&nbsp;<em>Bone And Joint Health Supplements Market, 2025\u20132033.<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>[4] Zhang Y, et al.&nbsp;<\/em><em>Osteoarthritis: molecular pathogenesis and potential therapeutic options.<\/em>&nbsp;<em>Signal Transduction and Targeted Therapy<\/em>, 2026.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">[5] Luo J, et al.&nbsp;<em>Systemic implications of osteoarthritis: from local degeneration to systemic metabolic dysregulation.<\/em>&nbsp;<em>Journal of Translational Medicine<\/em>, 2026.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">[6] Wu Z, et al.&nbsp;<em>Essential role of the metabolite \u03b1-ketoglutarate in bone tissue and bone-related diseases.<\/em>&nbsp;<em>Acta Biochimica et Biophysica Sinica<\/em>, 2025.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">[7] Wang Y, et al.&nbsp;<em>Alpha-ketoglutarate ameliorates age-related osteoporosis via regulating histone methylations.<\/em>&nbsp;<em>Nature Communications<\/em>, 2020<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">[8] He R, et al.&nbsp;<em>\u03b1-Ketoglutarate alleviates osteoarthritis by inhibiting ferroptosis via the ETV4\/SLC7A11\/GPX4 signaling pathway.<\/em>&nbsp;<em>Cellular &amp; Molecular Biology Letters<\/em>, 2024<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">[9] Long F, et al.&nbsp;<em>The research progress of \u03b1-ketoglutarate in osteoarthritis.<\/em>&nbsp;<em>Biochemistry and Biophysics Reports<\/em>, 2025<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">[10]&nbsp;<em>Chondrocyte inflammatory-immune responses in osteoarthritis: From pathogenesis to therapeutic intervention.<\/em>&nbsp;<em>International Immunopharmacology<\/em>, 2026.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">[11]&nbsp;<em>Pathogenesis and therapeutic strategies of osteoarthritis: roles of immune cells, inflammatory mediators, and pathogenic signaling pathways.<\/em>&nbsp;2026.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">[12] Hu Q, Ecker M.&nbsp;<em>Overview of MMP-13 as a Promising Target for the Treatment of Osteoarthritis.<\/em>&nbsp;<em>International Journal of Molecular Sciences<\/em>, 2021<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">[13]\u00a0Cheng HB, et al. C-Terminal Cross-Linked Telopeptides of Type II Collagen as Biomarkers for Radiological Knee Osteoarthritis: A Meta-Analysis. Cartilage, 2018.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u8fc7\u53bb\u51e0\u5e74\uff0cCa-AKG \u51e0\u4e4e\u59cb\u7ec8\u4e0e\u4e00\u4e2a\u5173\u952e\u8bcd\u7ed1\u5b9a \u2014\u2014Healthy Aging\uff08\u5065\u5eb7\u8870\u8001\uff09\u3002 \u4ece TCA \u5faa [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-4270","post","type-post","status-publish","format-standard","hentry","category-company-news"],"_links":{"self":[{"href":"https:\/\/www.hygieia.com.cn\/index.php?rest_route=\/wp\/v2\/posts\/4270","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hygieia.com.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hygieia.com.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hygieia.com.cn\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hygieia.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4270"}],"version-history":[{"count":4,"href":"https:\/\/www.hygieia.com.cn\/index.php?rest_route=\/wp\/v2\/posts\/4270\/revisions"}],"predecessor-version":[{"id":4283,"href":"https:\/\/www.hygieia.com.cn\/index.php?rest_route=\/wp\/v2\/posts\/4270\/revisions\/4283"}],"wp:attachment":[{"href":"https:\/\/www.hygieia.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4270"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hygieia.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4270"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hygieia.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4270"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}